Posts Tagged ‘fibrosis’

The Advantages and Disadvantages of Liver Fibrosis Evaluation Methods

Chronic liver disease severity is determined by the liver’s landscape; the more liver cells that are damaged and scarred, the more advanced the liver disease is. Even after an initial diagnosis, the current state of your liver’s tissue is a major factor for predicting prognosis and making ongoing therapeutic decisions. Liver biopsy is the globally…

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Now There Are Many (Stages)

Now There Are Many (Stages) Where Before There Was One: In Search of a Pathophysiological Classification of Cirrhosis Guadalupe Garcia-Tsao,1 Scott Friedman,2 John Iredale,3 and Massimo Pinzani4 For more than a century and a half, the description of a liver as “cirrhotic” was sufficient to connote both a pathological and clinical status, and to assign…

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NCKU team discovers new liver disease treatment

NCKU team discovers new liver disease treatment TAIPEI, Taiwan — A National Cheng Kung University (NCKU) team has discovered the pathogenesis of liver fibrosis and developed antibodies that reduce liver damage, inhibit hepatic fibrosis and recover liver function, according to a press release from the school. Ming-shi Chang, chair professor of biochemistry and molecular biology…

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Fast Track Designation for Fatty Liver Disease With Advanced Fibrosis

Fast Track  for Fatty Liver Disease With Advanced Fibrosis Galectin Therapeutics Receives FDA Fast Track Designation for GR-MD-02 for Fatty Liver Disease With Advanced Fibrosis  NORCROSS, Ga., Aug 12, 2013 (GLOBE NEWSWIRE via COMTEX) — Galectin Therapeutics GALT +21.72% , the leading developer of therapeutics that target galectin proteins to treat fibrosis and cancer, today…

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What is Fibrosis?

What is Fibrosis? Liver fibrosis is not an independent disease but rather a histological change caused by liver inflammation. Liver damage causes liver stellate cells to be over active and triggers the extra cellular matrix (ECM) synthesis to increase. More than normal amounts of collagen fiber deposits in the extra-cellular spaces of the liver cells…

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